Zebrafish made to grow pre-hands instead of fins








































PERHAPS the little fish embryo shown here is dancing a jig because it has just discovered that it has legs instead of fins. Fossils show that limbs evolved from fins, but a new study shows how it may have happened, live in the lab.













Fernando Casares of the Spanish National Research Council and his colleagues injected zebrafish with the hoxd13 gene from a mouse. The protein that the gene codes for controls the development of autopods, a precursor to hands, feet and paws.












Zebrafish naturally carry hoxd13 but produce less of the protein than tetrapods - all four-limbed vertebrates and birds - do. Casares and his colleagues hoped that by injecting extra copies of the gene into the zebrafish embryos, some of their cells would make more of the protein.












One full day later, all of those fish whose cells had taken up the gene began to develop autopods instead of fins. They carried on growing for four days but then died (Cell, DOI: 10.1016/j.devcel.2012.10.015).












"Of course, we haven't been able to grow hands," says Casares. He speculates that hundreds of millions of years ago, the ancestors of tetrapods began expressing more hoxd13 for some reason and that this could have allowed them to evolve autopods.


















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































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Karena Lam pregnant again






HONG KONG: Hong Kong actress Karena Lam revealed Saturday during a publicity event that she is pregnant with her second child, reported Hong Kong media.

The actress, who is married to advertisement director Steve Yuen, gave birth to their first, daughter Kayla, in 2010.

Lam expressed that she has asked actor Ekin Cheng, who was also at the event, to be her unborn child's godfather.

"We are discussing whether I can be the child's godfather, but we'll have to ask her husband first," said Cheng, adding that he hoped it will be a boy, and would teach the child martial arts if it turns out to be a boy.

"If it's a boy, I hope he is not as naughty as you," Lam quipped.

Cheng appeared very happy for his old friend, and posed like a pregnant mother in a goofy photo with her, which she promptly put up on her micro blog.

-CNA/ha



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iPhone 5 sales in China surpass 2 million in first weekend



Apple's iPhone 5.



(Credit:
CNET)


It's been just three days since Apple's iPhone 5 launch in China and already 2 million devices have already been sold. The tech giant announced today that this latest model of its popular smartphone is selling faster than ever in the Far East country.

"Customer response to
iPhone 5 in China has been incredible, setting a new record with the best first weekend sales ever in China," Apple CEO Tim Cook said in a statement. "China is a very important market for us and customers there cannot wait to get their hands on Apple products."

The iPhone 5 went on sale on Thursday in China and even before people could get their hands on the smartphone, hundreds of thousands of online reservations were already made for the device. The device is available through carriers China Telecom and China Unicom and, as of now, it's still not being offered on China Mobile -- the country's largest carrier.

China is of huge significance for Apple, it is the company's second biggest market -- after the U.S. -- and already accounted for about 15 percent ($23.8 billion) of the company's revenue for its fiscal year that ended in September.

When the iPhone 5 first launched in the U.S. in September, its sales topped 5 million units over first weekend -- which was a million higher than the
iPhone 4S. According to analysts at investment bank Canaccord Genuity, it is expected that Apple will sell 47.5 million iPhones in the current quarter, up from its prior forecast for 45 million. However, estimates for the first quarter of 2013 have been slightly lowered -- now 46 million instead of 47.5 million -- as the earlier-than-expected China launch is most likely pulling sales into this quarter.

Besides China, the iPhone 5 will also be on sale in more than 100 other countries by the end of the month. According to Apple, this makes the iPhone 5 the fastest iPhone rollout ever.

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Space Pictures This Week: Frosty Mars, Mini Nile, More

Photograph by Mike Theiss, National Geographic

The aurora borealis, also known as the northern lights, illuminates the Arctic sky in a recent picture by National Geographic photographer Mike Theiss.

A storm chaser by trade, Theiss is in the Arctic Circle on an expedition to photograph auroras, which result from collisions between charged particles released from the sun's atmosphere and gaseous particles in Earth's atmosphere.

After one particularly amazing show, he wrote on YouTube, "The lights were dancing, rolling, and twisting, and at times looked like they were close enough to touch!" (Watch his time-lapse video of the northern lights.)

Published December 14, 2012

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Obama Offers Newtown 'Love and Prayers of a Nation'













President Barack Obama said at an interfaith prayer service in this mourning community this evening that the country is "left with some hard questions" if it is to curb a rising trend in gun violence, such as the shooting spree Friday at Newtown's Sandy Hook Elementary School.


After consoling victims' families in classrooms at Newtown High School, the president said he would do everything in his power to "engage" a dialogue with Americans, including law enforcement and mental health professionals, because "we can't tolerate this anymore. These tragedies must end. And to end them we must change."






Mandel Ngan/AFP/Getty Images











President Obama: 'Newtown You Are Not Alone' Watch Video









Sandy Hook Elementary Shooting: Remembering the Victims Watch Video







The president was not specific about what he thought would be necessary and did not even use the word "gun" in his remarks, but his speech was widely perceived as prelude to a call for more regulations and restrictions on the availability of firearms.


The grieving small town hosted the memorial service this evening as the the nation pieces together the circumstances that led to a gunman taking 26 lives Friday at the community's Sandy Hook Elementary School, most first graders.


"Someone once described the joy and anxiety of parenthood as the equivalent of having your heart outside your body all of the time, walking around," he said, speaking of the joys and fears of raising children.


"So it comes as a shock at a certain point when you realize no matter how much you love these kids you can't do it by yourself," he continued. "That this job of protecting kids and teaching them well is something we can only do together, with the help of friends and neighbors, with the help of a community, and the help of a nation."


CLICK HERE for Full Coverage of the Tragedy at Sandy Hook






Read More..

Zebrafish made to grow pre-hands instead of fins








































PERHAPS the little fish embryo shown here is dancing a jig because it has just discovered that it has legs instead of fins. Fossils show that limbs evolved from fins, but a new study shows how it may have happened, live in the lab.













Fernando Casares of the Spanish National Research Council and his colleagues injected zebrafish with the hoxd13 gene from a mouse. The protein that the gene codes for controls the development of autopods, a precursor to hands, feet and paws.












Zebrafish naturally carry hoxd13 but produce less of the protein than tetrapods - all four-limbed vertebrates and birds - do. Casares and his colleagues hoped that by injecting extra copies of the gene into the zebrafish embryos, some of their cells would make more of the protein.












One full day later, all of those fish whose cells had taken up the gene began to develop autopods instead of fins. They carried on growing for four days but then died (Cell, DOI: 10.1016/j.devcel.2012.10.015).












"Of course, we haven't been able to grow hands," says Casares. He speculates that hundreds of millions of years ago, the ancestors of tetrapods began expressing more hoxd13 for some reason and that this could have allowed them to evolve autopods.


















































If you would like to reuse any content from New Scientist, either in print or online, please contact the syndication department first for permission. New Scientist does not own rights to photos, but there are a variety of licensing options available for use of articles and graphics we own the copyright to.




































All comments should respect the New Scientist House Rules. If you think a particular comment breaks these rules then please use the "Report" link in that comment to report it to us.


If you are having a technical problem posting a comment, please contact technical support.








Read More..

Body found in Singapore River






SINGAPORE: A man was found dead in the Singapore River along Clarke Quay early Sunday morning.

The Singapore Civil Defence Force (SCDF) said it received a call at about 1.30am.

Someone was spotted jumping into the river near Block A.

SCDF officers arrived about four minutes later and conducted a search around the area.

Diving at a depth of about 3 metres, rescuers retrieved the body of a man about three-and-a-half hours later.

He was pronounced dead at the scene.

Police are investigating the unnatural death.

- CNA/ir



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Google will alter search to end FTC antitrust inquiry, says report



The Federal Trade Commission may bring its two-year antitrust investigation of Google to a close by allowing the company to make voluntary changes to its search business, according to a report.


The search giant is said to be readying an announcement about changes to its use of "snippets," bits of text culled from sites such as Yelp and TripAdvisor and displayed in search results, Politico reports, citing unnamed sources. Yelp and others had charged Google with using their content without permission.


Google will also makes tweaks that will allow for easier porting of search-ad campaigns from Google to rival search services, Politico's sources said.



Politico suggested on Tuesday that the FTC may leave the search-related case to the European Commission, which has mounted an investigation of its own. Reuters reported on Tuesday that some Google competitors, sensing a possible defeat, are taking the case to the Justice Department.


Google and the FTC also look to be close to a settlement in a case involving so-called frand -- or standard essential -- patents owned by Google.


Politico said the FTC declined to comment on today's report about the search tweaks, and it said Google would provide only the following statement: "We continue to work cooperatively with the Federal Trade Commission and are happy to answer any questions they may have."


Read More..

Space Pictures This Week: Frosty Mars, Mini Nile, More

Photograph by Mike Theiss, National Geographic

The aurora borealis, also known as the northern lights, illuminates the Arctic sky in a recent picture by National Geographic photographer Mike Theiss.

A storm chaser by trade, Theiss is in the Arctic Circle on an expedition to photograph auroras, which result from collisions between charged particles released from the sun's atmosphere and gaseous particles in Earth's atmosphere.

After one particularly amazing show, he wrote on YouTube, "The lights were dancing, rolling, and twisting, and at times looked like they were close enough to touch!" (Watch his time-lapse video of the northern lights.)

Published December 14, 2012

Read More..

Conn. Victim's Father Remembers 'Loving' Daughter


ht emilie parker wy 121215 wblog Emilie Parker: Sandy Hook Victim Would Have Comforted Classmates, Dad Says

(Image credit: Emilie Parker Fund/Facebook)


Emilie Parker, the little girl with the blond hair and bright blue eyes, would have been one of the first to comfort her classmates at Sandy Hook Elementary School, had a gunman’s bullets not claimed her life, her father said.


“My daughter Emilie would be one of the first ones to be standing and giving support to all the victims because that’s the kind of kid she is,” her father, Robbie Parker said as he fought back tears, telling the world about his “bright, creative and loving” daughter who was one of the 20 young victims in the Newtown, Conn., shooting.


“She always had something kind to say about anybody,” her father said.  ”We find comfort reflecting on the incredible person Emilie was and how many lives she was able to touch.”


Emilie, 6, was helping teach her younger sisters to read and make things, and she was the little girls would go to for comfort, he said.


“They looked up to her,” Parker said.


READ: Complete List of Sandy Hook Victims


Parker moved his wife and three daughters to Newtown eight months ago after accepting a job as  a physician’s assistant at Danbury Hospital. He said Emilie, his oldest daughter, seemed to have adjusted well to her new school, and he was very happy with the school, too.


“I love the people at the school. I love Emilie’s teacher and the classmates we were able to get to know,” he said.


ap shock newton shooting sandy hook lpl 121214 wblog Emilie Parker: Sandy Hook Victim Would Have Comforted Classmates, Dad Says

      (Image Credit: Alex von Kleydorff/AP Photo)


The family dealt with another tragic loss in October when Emilie lost her grandfather in an accident.


“[This] has been a topic that has been discussed in our family in the past couple of  months,” Parker said. “[My daughters ages 3 and 4] seem to get the idea that there’s somebody who they will miss very much.”


Emilie, a budding artist who carried her markers and pencils everywhere, paid tribute to her grandfather by slipping a special card she had drawn into his casket, Parker said.  It was something she frequently did to lift the spirits of others.


“I can’t count the number of times Emilie would find someone feeling sad or frustrated and would make people a card,” Parker said. “She was an exceptional artist.”


The girl who was remembered as “always willing to try new things, other than food” was learning Portuguese from her father, who speaks the language.


ht emilie parker 2 121215 wblog Emilie Parker: Sandy Hook Victim Would Have Comforted Classmates, Dad Says

(Image Credit: Emilie Parker Fund/Facebook)


On Friday morning, Emilie woke up before her father left for his job and exchanged a few sentences with him in the language.


“She told me good morning and asked how I was doing,” Parker said. “She said she loved me, I gave her a kiss and I was out the door.”


Parker found out about the shooting while on lockdown in Danbury Hospital and found a television for the latest news.


“I didn’t think it was that big of deal at first,” he said. “With the first reports coming in, it didn’t sound like it was going to be as tragic as it was. That’s kind of what it was like for us.”


CLICK HERE for full coverage of the Sandy Hook shooting.


Parker said he knows that God can’t take away free will and would have been unable to stop the Sandy Hook shooting. While gunman Adam Lanza used his free agency to take innocent lives, Parker said he plans to use his in a positive way.


“I’m not mad because I have my  [free] agency to use this event to do whatever I can to make sure my family and my wife and my daughters are taken care [of],” he said. “And if there’s anything I can do to help to anyone at any time at anywhere, I’m free to do that.”


ht emilie parker 3 121215 wblog Emilie Parker: Sandy Hook Victim Would Have Comforted Classmates, Dad Says

(Image credit: Emilie Parker Fund/Facebook)


Friday night, hours after he learned of his daughter’s death, Parker said he spoke at his church.


“I don’t know how to get through something like this. My wife and I don’t understand how to process all of this,” he said today. “We find strength in our religion and in our faith and in our family. ”


“It’s a horrific tragedy and I want everyone to know our hearts and prayers go out to them. This includes the family of the shooter. I can’t imagine how hard this experience must be for you and I want you to know our family … love and support goes out to you as well.”

Read More..